Private beta · Precision wellness
Onceby
Clinical-grade AI that builds your supplement and skincare protocol, checked for every interaction.
Limited cohort onboarding. Evidence-backed. DESIGNED WITH SAFETY CHECKS.
01 — The science
One profile, one verified protocol
Onceby protocol synthesis
Sample session 0042
01 / Profile inputs
Profile
34 · Female · Product lead
Location
London · 51.5°N
Sleep
52 min latency · 5 h 40 m
25(OH)D
19 ng/mL
Ferritin
22 ng/mL
Medication
Combined oral contraceptive
Skin
Dry, barrier-impaired
02 / RAG clinical engine
[Cross-referencing 10,420 PubMed records…]
[Retrieving: vitamin D status, 51°N in winter]
[Retrieving: ferritin under 30 and fatigue]
[Mapping: magnesium and sleep-onset latency]
[Interaction check: 14 rules]
Passed
10,420
Studies scanned for this profile
03 / Output stack
Vitamin D3 2,000 IU + K2 100 mcg
AM · PMID 30275418
Iron bisglycinate 25 mg, alternate days
AM · PMID 29032957
Magnesium glycinate 300 mg
PM · PMID 23853635
Ceramide barrier cream, nightly
Topical · PM
14 checks passed · No conflicts
02 — The problem
More pills, fewer answers
Consumers spend $1,000+ annually on supplements and dermatological products, yet 74% consume bio-antagonistic combinations that cancel clinical efficacy or trigger sub-acute inflammation.
Option A
Generic quizzes and influencer stacks
One quiz for everyone, built to sell a bundle.
Overlapping supplements
unbalanced DOSES
No labs, no timing
Option B
Unchecked AI chatbots
Fluent answers with no sources and real hallucination risk.
No citations
No interaction checks
Confident, unverified doses
Onceby
The Clinical RAG Engine
Retrieval from cited trials, then deterministic safety checks.
Every pick cited
Actives and minerals checked
AM/PM timing built in
03 — How it works
From intake to safe protocol
01
Clinical intake
Symptoms · Labs · Meds · Skin · Location
02
Evidence synthesis
PubMed · RCTs · Meta-analyses
03
Safety guardrails
Dose ceilings · CYP450 · Actives
04
Your protocol
AM/PM · Doses · Brands · PMIDs
04 — Safety guardrails
Three people, three checked protocols
Burnout & sleep
Acne & gut-skin
Longevity
Burnout and sleep latency
Maya, 34 · Product lead · London
Illustrative sample
Sleep latency
52 min
Avg sleep
5 h 40 m
25(OH)D
19 ng/mL
Ferritin
22 ng/mL
Diagnostic ledger
Vitamin D insufficiency
19 ng/mL · low winter UV at 51°N
High
Low iron stores
Ferritin 22 · afternoon crashes
Moderate
Magnesium-linked sleep onset
52 min latency · night cramps
Moderate
Supplements
AM · with breakfast
Vitamin D3 + K2 · 2,000 IU / 100 mcg
Thorne · PMID 30275418
Iron bisglycinate · 25 mg, alternate days
Thorne · PMID 29032957
PM · 60 min before bed
Magnesium glycinate · 300 mg
Pure Encapsulations · PMID 23853635
L-theanine · 200 mg
Thorne · PMID 31623400
Topicals
AM routine
Ceramide moisturiser
CeraVe · Moisturising Cream
Broad-spectrum SPF 50
La Roche-Posay Anthelios · PMID 23732711
PM routine
Ceramide + niacinamide lotion
CeraVe · PM Facial Lotion
Conflict prevented
St John’s wort blocked: it can make your oral contraceptive less effective.
Rule DN-031 · CYP3A4 induction
Sample data · Any third-party-tested equivalent works · Not medical advice
05 — Questions
Straight answers, before you join
How does Onceby prevent AI hallucinations?
Where does your clinical data come from?
Do you recommend specific brands?
Is this medical advice?
Onceby is for informational and educational wellness decision-support. It is not a formal medical diagnosis or a substitute for professional care.
06 — Private beta
Join the first cohort
Reserve your place in Cohort #1. Evidence-backed protocols, onboarded in small groups.